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10.1016/j.amjcard.2007.05.022

Seeing GLP-1 present in the joint environment opens up the possibility that its role extends beyond metabolic pathways into local inflammatory modulation

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Another recently discovered mechanism by which proteins and particulates and possibly bacteria can penetrate the mucosa is via GAPs, in which large solutes such as 10 kDa dextran and proteins such as albumin traverse the mucosa where they are presented to subepithelial dendritic cells [19, 53, 62]